Treat a deep second-degree burn healing with Persian Turpentine

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Wounds resulting from burns, considering their cause and extent, are among chronic wounds. Burn wounds, such as deep 2nd-degree burns, require special care to heal because they cannot be healed with stitches or traditional dressings.

For the patient to be properly treated, it is necessary to perform different clinical tests on him/her.

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Burn wound healing with Persian Turpentine

To date (Sunday – 2023 01 October), no known approach has been identified for its successful wound-healing activity and its ability to initiate distinct molecular and cellular mechanisms in various types of wounds.

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Hence, it is necessary to find an alternative treatment with minimal side effects.

Several studies employing medicinal plants have recently discussed the creation of new resources and technologies with the potential to heal a variety of acute and chronic wounds with minimum side effects, ease of administration, increased efficacy, and cheaper treatment costs for patients.

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How to treat 2nd degree burn healing by Persian Turpentine , Treat a deep second-degree burn healing with Persian Turpentine
How to treat 2nd degree burn healing by Persian Turpentine , Treat a deep second-degree burn healing with Persian Turpentine

The First Study (2013)

A study (2013) was conducted to evaluate the effect of Pistacia atlantica resin (Persian Turpentine) extract on the rat skin burn wound healing.

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«The results showed that the Pistacia atlantica resin (Mount Atlas Mastic Liquid) extract has a concentration-dependent effect on the healing of burn wounds after 14 days of treatment by increasing the concentration of bFGF (basic fibroblast growth factor) and PDGF (platelet derived growth factor) and also through improving the angiogenesis

The Second Study (2018)

Another study (2018) was conducted to evaluate the effect of Pistacia atlantica resin oil on Anti-Oxidant, Hydroxyprolin and VEGF (vascular endothelial growth factor) Changes in Experimentally-Induced Skin Burn in Rat.

VEGF levels in burn wound area. Group 1, burn control; group 2, burn-treated with P. atlantica resin oil topically; group 3, burn-treated with sulfadiazine. *statistically significant compared to Burn control group, #statistically significant compared to burn-treated with sulfadiazine group
VEGF levels in burn wound area. Group 1, burn control; group 2, burn-treated with P. atlantica resin oil topically; group 3, burn-treated with sulfadiazine. *statistically significant compared to Burn control group, #statistically significant compared to burn-treated with sulfadiazine group

«The results showed that the P. Atlantica oil significantly increased antioxidant defense, VEGF (vascular endothelial growth factor), hydroxyprolin and reduced MDA (malondialdehyde) levels. It could remarkably reduce wound size compared to burn control group (sulfadiazine cream)

The P. Atlantica oil (Turpentine Oil) showed more beneficial effects than sulfadiazine.

Hydroxyproline levels in burn wound area. Group 1, burn control; group 2, burn-treated with P. atlantica resin oil topically; group 3, burn-treated with sulfadiazine. *statistically significant compared to Burn control group, # statistically significant compared to burn-treated with sulfadiazine group
Hydroxyproline levels in burn wound area. Group 1, burn control; group 2, burn-treated with P. atlantica resin oil topically; group 3, burn-treated with sulfadiazine. *statistically significant compared to Burn control group, # statistically significant compared to burn-treated with sulfadiazine group

In summary, the P. atlantica resin oil could be considered as a new therapeutic agent for treatment of injuries.

Burn wound infection bacteria

Burn wound infections encompass more than half of mortalities per year, and several pathogenic microbes such as S. aureus, P. aeruginosa, and Escherichia coli, as well as coagulase-negative Staphylococci, have been identified in post-burn injuries.

Microbial colonies such as Staphylococcus aureus and Pseudomonas aeruginosa often invade chronic wounds, forming biofilms and leading to critical infections as well as impacting the overall process of wound repair.

They secrete endotoxins and exotoxins while modulating several immune responses at the wound site, producing excessive proteases that could degrade the extracellular matrix and impede the overall process of wound healing.

Factors affecting wound healing

Both intrinsic and extrinsic variables, such as the following can cause a wound to take longer to recover:

  • Drugs
  • Poor diet
  • Poor sleep habits
  • Less exercise
  • A high predilection for the use of alcohol and cigarettes
  • Comorbidities
  • Incorrect dressing options

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